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Index > Protein center > Slc1a2(Gene name) > Mouse
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  • Slc1a2 (Gene name),
  • Excitatory amino acid transporter 2 (Protein name ),  EAA2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Slc1a2(Eaat2;Glt1);
    Protein name:
    Excitatory amino acid transporter 2;
    Alternative:
    Sodium-dependent glutamate/aspartate transporter 2;GLT-1;Solute carrier family 1 member 2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homotrimer (By similarity). Interacts with JUB.
    Function:
    Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    572
    Sequence:
    50:
    MASTEGANNM | PKQVEVRMHD | SHLSSDEPKH | RNLGMRMCDK | LGKNLLLSLT | 
    100:
    VFGVILGAVC | GGLLRLASPI | HPDVVMLIAF | PGDILMRMLK | MLILPLIISS | 
    150:
    LITGLSGLDA | KASGRLGTRA | MVYYMSTTII | AAVLGVILVL | AIHPGNPKLK | 
    200:
    KQLGPGKKND | EVSSLDAFLD | LIRNLFPENL | VQACFQQIQT | VTKKVLVAPP | 
    250:
    SEEANTTKAV | ISMLNETMNE | APEETKIVIK | KGLEFKDGMN | VLGLIGFFIA | 
    300:
    FGIAMGKMGE | QAKLMVEFFN | ILNEIVMKLV | IMIMWYSPLG | IACLICGKII | 
    350:
    AIKDLEVVAR | QLGMYMITVI | VGLIIHGGIF | LPLIYFVVTR | KNPFSFFAGI | 
    400:
    FQAWITALGT | ASSAGTLPVT | FRCLEDNLGI | DKRVTRFVLP | VGATINMDGT | 
    450:
    ALYEAVAAIF | IAQMNGVILD | GGQIVTVSLT | ATLASIGAAS | IPSAGLVTML | 
    500:
    LILTAVGLPT | EDISLLVAVD | WLLDRMRTSV | NVVGDSFGAG | IVYHLSKSEL | 
    550:
    DTIDSQHRMQ | EDIEMTKTQS | IYDDKNHRES | NSNQCVYAAH | NSVVIDECKV | 
    572:
    TLAANGKSAD | CSVEEEPWKR | EK
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    UniGene:
    Pfam:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Excitatory amino acid transporter 2
    Cat.:
    E15494r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Excitatory amino acid transporter 2
    Cat.:
    E15494h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Excitatory amino acid transporter 2
    Cat.:
    E15494m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Excitatory amino acid transporter 2
    Cat.:
    U15494h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Excitatory amino acid transporter 2
    Cat.:
    U15494m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Excitatory amino acid transporter 2
    Cat.:
    U15494r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Excitatory amino acid transporter 2
    Cat.:
    P15494Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Excitatory amino acid transporter 2
    Cat.:
    P15494Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Excitatory amino acid transporter 2
    Cat.:
    P15494Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Excitatory amino acid transporter 2
    Monoclonal Antibody for Mouse Excitatory amino acid transporter 2
    Monoclonal Antibody for Mouse Excitatory amino acid transporter 2
    Protein for Mouse Excitatory amino acid transporter 2
    Protein for Mouse Excitatory amino acid transporter 2
    Protein for Mouse Excitatory amino acid transporter 2

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Mouse excitatory amino acid transporter EAAT2: isolation, characterization, and proximity to neuroexcitability loci on mouse chromosome 2."
      Kirschner M.A. , Copeland N.G. , Gilbert D.J. , Jenkins N.A. , Amara S.G.
      Genomics24:218-224(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6.
      tissue: Brain.
    2. 2.
      "Molecular cloning of two glutamate transporter subtypes from mouse brain."
      Mukainaka Y. , Tanaka K. , Hagiwara T. , Wada K.
      Biochim. Biophys. Acta1244:233-237(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: JCL:ICR.
      tissue: Cerebellum.
    3. 3.
      "Molecular characterization of a high-affinity mouse glutamate transporter."
      Sutherland M.L. , Delaney T.A. , Noebels J.L.
      Gene162:271-274(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6.
      tissue: Brain.
    4. 4.
      Peng J.-B. , Guo L.-H.
      Submitted (1997-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    5. 5.
      "Tissue specific variants of glutamate transporter GLT-1."
      Utsunomiya-Tate N. , Endou H. , Kanai Y.
      FEBS Lett.416:312-316(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];ALTERNATIVE SPLICING
      strain: JCL:ICR.
      tissue: Brain.
      tissue: Liver.
    6. 6.
      Lubec G. , Kang S.U.
      Submitted (2007-04) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 66-87; 159-173 AND 478-525;IDENTIFICATION BY MASS SPECTROMETRY
      strain: C57BL/6.
      tissue: Brain.
    7. 7.
      "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
      Ballif B.A. , Carey G.R. , Sunyaev S.R. , Gygi S.P.
      J. Proteome Res.7:311-318(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-537;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
    8. 8.
      "Palmitoylation and function of glial glutamate transporter-1 is reduced in the YAC128 mouse model of Huntington disease."
      Huang K. , Kang M.H. , Askew C. , Kang R. , Sanders S.S. , Wan J. , Davis N.G. , Hayden M.R.
      Neurobiol. Dis.40:207-215(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PALMITOYLATION AT CYS-38;MUTAGENESIS OF CYS-38
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